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MOTS-c treatment in mice has been shown to significantly enhance physical performance across different age groups, including young, middle-aged, and old mice

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Summary Keywords anxiety, autism, depression, eating disorders, food addiction, lipid metabolism, mental health, neuroinflammation Citation Poon E, Li C, Schweitzer D and Akefe I (2026) Neurobiological insights into the effects of ultra-processed food on lipid metabolism and associated mental health conditions: a scoping review

Indeed, since the pituitary has a substantial DRD2 reserve for PRL inhibition, and PRL response reaches the plateau at about 40% receptor occupancy in rat pituitary cells ( Since FLNA is crucial for both DRD2 expression and signaling in lactotrophs, the loss of FLNA expression may be one of the mechanisms involved in loss of DA responsiveness previously documented in human prolactinomas